Some physicians believe that Potter sequence is a more appropriate name than Potter syndrome because while the signs and symptoms can vary among affected newborns, the sequence of events that leads to the development of this condition is the same. Potter syndrome is an extremely serious condition and is often fatal at or shortly after birth, mainly due to the pulmonary hypoplasia. Sometimes, later during gestation, there may be amniotic fluid leakage this will not lead to Potter syndrome.
Potter syndrome can also result from other conditions including polycystic kidney disease, malformed (dysplastic) or underdeveloped (hypoplastic) kidneys, and obstructive uropathy, in which urine cannot be voided from the bladder and builds up within the kidneys. This is sometimes referred to as classic Potter syndrome. Most often, this condition is caused by absence of both kidneys (bilateral renal agenesis). When oligo-anhydramnios is present from early in pregnancy, the lungs are also underdeveloped (pulmonary hypoplasia), which can lead to severe breathing difficulties. When there is too little amniotic fluid normal pressure that is exerted on the fetus during pregnancy can cause certain physical features such as distinctive facial features or skeletal abnormalities. Amniotic fluid supports, cushions, and protects a developing fetus. Insufficient amounts of amniotic fluid during pregnancy is called oligohydramnios the absence of amniotic fluid is called anhydramnios.
Potter syndrome is a rare condition characterized by the physical characteristics of a fetus that develop when there is too little amniotic fluid in the uterus ( in utero) during pregnancy.
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